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Best 45601 Ohio Public High Schools (2026)

For the 2026 school year, there are 7 public high schools serving 3,136 students in 45601, OH.
The top-ranked public high schools in 45601, OH are Southeastern High School, Unioto High School and Chillicothe High School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.
Public high schools in zipcode 45601 have an average math proficiency score of 32% (versus the Ohio public high school average of 40%), and reading proficiency score of 57% (versus the 57% statewide average). High schools in 45601, OH have an average ranking of 4/10, which is in the bottom 50% of Ohio public high schools.
Public high school in zipcode 45601 have a Graduation Rate of 89%, which is more than the Ohio average of 86%.
The school with highest graduation rate is Southeastern High School, with ≥95% graduation rate. Read more about public school graduation rate statistics in Ohio or national school graduation rate statistics.
Minority enrollment is 12% of the student body (majority Black), which is less than the Ohio public high school average of 33% (majority Black).

Best 45601, OH Public High Schools (2026)

School
(Math and Reading Proficiency)
Location
Quick Facts
Rank: #11.
Southeastern High School
(Math: 50-54% | Reading: 65-69%)
Rank:
6/
10
Top 50%
2003 Lancaster Rd
Chillicothe, OH 45601
(740) 774-2003
Gr: 9-12 | 251 students Student-teacher ratio: 11:1 Minority enrollment: 4%
Rank: #22.
Unioto High School
(Math: 40-44% | Reading: 65-69%)
Rank:
5/
10
Bottom 50%
14193 Pleasant Valley Rd
Chillicothe, OH 45601
(740) 773-4105
Gr: 9-12 | 605 students Student-teacher ratio: 26:1 Minority enrollment: 10%
Rank: #33.
Chillicothe High School
(Math: 25-29% | Reading: 58%)
Rank:
4/
10
Bottom 50%
421 Yoctangee Pkwy
Chillicothe, OH 45601
(740) 702-2287
Gr: 9-12 | 859 students Student-teacher ratio: 20:1 Minority enrollment: 25%
Rank: #44.
Zane Trace High School
(Math: 30-34% | Reading: 45-49%)
Rank:
3/
10
Bottom 50%
946 State Route 180
Chillicothe, OH 45601
(740) 775-1809
Gr: 9-12 | 363 students Student-teacher ratio: 21:1 Minority enrollment: 6%
Rank: #55.
Huntington High School
(Math: 25-29% | Reading: 40-44%)
Rank:
3/
10
Bottom 50%
188 Huntsman Rd
Chillicothe, OH 45601
(740) 663-2230
Gr: 9-12 | 306 students Student-teacher ratio: 14:1 Minority enrollment: 4%
Rank: n/an/a
Pickaway-ross Career & Technology Center
Vocational School
895 Crouse Chapel Rd
Chillicothe, OH 45601
(740) 642-1200
Gr: 7-12 | 710 students Minority enrollment: 6%
Rank: n/an/a
Southern Ohio Career Academy
Charter School
30 E Main St
Chillicothe, OH 45601
(330) 620-5861
Gr: 9-12 | 42 students Student-teacher ratio: 11:1 Minority enrollment: 29%
[+] Show Closed Public Schools in 45601 Ohio

45601, Ohio Public Schools (Closed)

School
Location
Quick Facts
174 Plyleys Ln
Chillicothe, OH 45601
(740) 774-1119
Gr: PK-6 | 426 students Student-teacher ratio: 20:1 Minority enrollment: 16%
40 W 5th St
Chillicothe, OH 45601
(740) 772-2346
Gr: PK-5 | 249 students Minority enrollment: 23%
101 University Dr
Chillicothe, OH 45601
(740) 775-4250
77 Cutright Dr
Chillicothe, OH 45601
(740) 774-3395
Gr: PK-5 | 242 students Student-teacher ratio: 19:1 Minority enrollment: 16%
1432 Egypt Pike
Chillicothe, OH 45601
(740) 773-4104
Gr: 5-6 | 290 students Student-teacher ratio: 17:1 Minority enrollment: 4%
1049 Columbus St
Chillicothe, OH 45601
(740) 774-2129
Gr: PK-5 | 279 students Minority enrollment: 16%
235 Cherry St
Chillicothe, OH 45601
(740) 775-4250
Gr: PK | 53 students Student-teacher ratio: 27:1 Minority enrollment: 13%
450 Allen Ave
Chillicothe, OH 45601
(740) 774-3307
Gr: PK-6 | 368 students Student-teacher ratio: 18:1 Minority enrollment: 30%
<麻豆果冻传媒 class='so-dt-title' id='faq'>Frequently Asked Questions
What are the top-ranked public high schools in 45601, OH?
The top-ranked public high schools in 45601, OH include Southeastern High School, Unioto High School and Chillicothe High School.
How many public high schools are located in 45601?
7 public high schools are located in 45601.
What is the racial composition of students in 45601?
45601 public high schools minority enrollment is 12% of the student body (majority Black), which is less than the Ohio public high schools average of 33% (majority Black).

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